- Dams, Waterways, & Docks Contractors, Clarkston
- Dance Companies, Clarkston
- Data Recovery Services, Clarkston - Hard Drive Data Recovery, etc
- Day Spas, Clarkston
- Deck, Patio & Gazebo Design, Building, Cleaning, Repair & Maintenance Contractors, Clarkston
- Decorating & Designing Services, Clarkston
- Decorative & Stamped Concrete, Clarkston
- Delicatessen Restaurants, Clarkston
- Dental Bonding & Cosmetic Dentistry, Clarkston - Cosmetic Dentist & Tooth Bonding
- Dentists, Clarkston
- Denturists, Clarkston
- Department Stores, Clarkston
- Dermatologists, Clarkston - Skin Doctors, Physicians & Surgeons (Dermatology)
- Developmental Disabilities, Clarkston
- Developmentally Disabled Information & Services, Clarkston
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- Diabetes Services & Supplies, Clarkston - Educational, Referral & Support Service Centers
- Dialysis Clinics, Clarkston - Kidney Dialysis Centers
- Direct Selling Businesses, Clarkston
- Disabled Persons Assistive Services, Clarkston
- Disc Jockeys, Clarkston
- Discount Stores, Clarkston - Clothing, Grocery, Furniture, Etc
- Divorce & Family Law Attorneys & Lawyers, Clarkston
- Doctors, Physicians & Surgeons, Clarkston
- Donuts, Clarkston
- Drinking Establishments, Clarkston
- Drive In Restaurants, Clarkston
- Driveway, Parking Lot & Blacktop Contractors, Clarkston - Construction, Repair & Maintenance
- Dry Cleaning & Laundry, Clarkston - Dry Cleaners
- Drywall, Insulation & Plaster Contractors, Clarkston - Installation & Repair Services
- Durable & Non Durable Goods & Products, Clarkston
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